This is a firm favourite in Manchester and has a big loyal fanbase. The downstairs may not seem very hidden with its skater shop 80s style skateboards serving as seats. But its the upstairs that the magic happens.

Disguised by a stack of wooden beer crates lies Science and Industry, a cocktail laboratory complete with its own chemistry workshop, serving some seriously delicious cocktails.

Cane and Grain, 49-51 Thomas Street, Manchester M4 1N

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